11/5/2023 0 Comments Agilent software chemstationIn the allergic airway inflammation model, the intranasal administration of the strain decreased type 2 inflammation and enhanced epithelial barrier integrity from the airways. sakei HEM 224 improved colitis physiology with immunomodulation, enhancing barrier components and gut microbiota alteration. In the colitis model, oral administration of L. a murine model with colitis induced by dextran sulfate sodium (DSS) and an allergic airway inflammation model induced by ovalbumin (OVA). The probiotic potential of strain HEM 224 in diverse mucosal areas was shown in two different models, viz. sakei HEM 224 showed negative results for hemolysis, biogenic amine production and transferable antibiotic resistance. Lactobacillus sakei HEM 224 was isolated from traditional Korean kimchi and identified. ![]() This study aimed to isolate and evaluate a putative probiotic strain on various mucosal regions. Mucosal tissues serve as the first defense line and their commensal microbiota play a role in sustaining of host health.
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